Jgriffin187, my kit fits in front of the left-rear tire, therefore cab configuration makes zero difference.
as for a drain, i don't have an accurate answer for you. i believe water will pass through the CAT, per George Morrison's info. if so you'll be just fine. i've contemplated making another bracket that can hold 2 filters, a small racor w/ heat & water (30um) and the big CAT. however the racor assembly is about $200+ if i remember and that makes it an expensive option... i've got other CAT solutions for heaters, but not water. i asked my CAT guy today and he thought the water would pass through it also.. do you find a lot of water in your OEM filter during the winter? i know i'm in Cali, but i've never seen a drop in my oem..