Is there any interfearence with the subject tire size on a classic '07 4X4 crew 2500? Thanks in advance

I have 285 75 16's on mine sitting stock and have never heard them rub. So I assume you should be alright.

If you have front mud flats the tires may rub when backing up with full lock steering turn.

I agree with RVC.

One item to note, I have 2 sets of identical tires on 2 seperate rims and one set is on the stock rim and one set on a 16x8 aftermarket rim, both with 4.5" backspacing. 265/75/16 is my size BTW

The stock set does and did not rub, the aftermarket set did until I experienced some tire wear.

Again as RVC stated, only backing up near or at full lock.

I run 265/75/16 AT Toyo's and have no problem.

285/75/16 on stock rims very slight rub when locked hard left

No problem here. Check garage for pics.

If you have front mud flats the tires may rub when backing up with full lock steering turn.
Only issue I ran into . . . but one extra screw and that was fixed.