Whats everyone run there setting for defuel between shifts, I just put the edge on my truck I like the power and was wondering if turning the defuel off during shifts would hurt the tranny in the long run. I run the truck on level 3.

Also it has the low boost setting for smoke, is it ok to leave it on 5 for most response and most smoke?

keep the defuel on, you will save your trans in the end even if you arent runing big power.